PLA2G10 Human shRNA Plasmid Kit (Locus ID 8399)
Specifications
| Product Data | |
| Locus ID | 8399 |
|---|---|
| Synonyms | SPLA2, GXPLA2, GXSPLA2, MGC119918, MGC119919 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PLA2G10 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 8399). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001031688, NM_003561, NR_133651, NM_003561.1, NM_003561.2, BC106731, BC069539, BC106732, BC111804, BM739473, NM_003561.3 |
| UniProt ID | O15496 |
| Summary | This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. provided by RefSeq, Nov 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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