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MARCH2 Human shRNA Plasmid Kit (Locus ID 51257)

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SKU
TR315142
MARCH2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 51257
Synonyms HSPC240; MARCH-II; MARCH2; RNF172
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components MARCH2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 51257). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001005415, NM_001005416, NM_016496, NM_016496.1, NM_016496.2, NM_016496.3, NM_016496.4, NM_001005415.1, NM_001005416.1, BC032624, BC032624.1, BC015910, BC111388, NM_001369776, NM_001369779, NM_001369777, NM_001369778, NR_163145, NM_001005416.2
UniProt ID Q9P0N8
Summary MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 PubMed 14722266; Nakamura et al., 2005 PubMed 15689499).supplied by OMIM, Mar 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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