MRP6 (ABCC6) Human shRNA Plasmid Kit (Locus ID 368)

SKU
TR315023
ABCC6 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 368
Synonyms ABC34; ARA; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components ABCC6 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 368). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001079528, NM_001171, NM_001351800, NR_147784, NM_001171.1, NM_001171.2, NM_001171.3, NM_001171.4, NM_001171.5, NM_001079528.1, NM_001079528.2, NM_001079528.3, BC050733, BC131732, NM_001079528.4
UniProt ID O95255
Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Dysregulation of gene expression in ABCC6 knockdown HepG2 cells
Miglionico, Armentano, Carmosino et al
Cell. Mol. Biol. Lett. (2014)
Cited by 32
AI Summary: OriGene Technologies contributed to this study by providing four ABCC6-targeting shRNAs and a scrambled shRNA (all cloned into the pRS vector), which were used to generate ABCC6 knockdown HepG2 cells for gene expression analysis.
Snippet: Four short-hairpin RNAs (shRNAs) targeting different sequences in the coding regions of the ABCC6 gene (ABCC6-shRNA) and a scrambled shRNA (scr-shRNA) cloned into the pRS vector were purchased from OriGene Technologies. ... Cite SaveSaving
Showing 1-1 of 1 papers.
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