AOC2 Human shRNA Plasmid Kit (Locus ID 314)
Specifications
| Product Data | |
| Locus ID | 314 |
|---|---|
| Synonyms | DAO2; RAO; SSAO |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | AOC2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 314). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001158, NM_009590, NM_001158.1, NM_001158.2, NM_001158.3, NM_001158.4, NM_009590.1, NM_009590.2, NM_009590.3, BC142641, NM_001158.5, NM_009590.4 |
| UniProt ID | O75106 |
| Summary | Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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