OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

AP2 alpha (AP2A1) Human shRNA Plasmid Kit (Locus ID 160)

Be the first to review this product
SKU
TR314754
AP2A1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

Frequently Bought Together (2)

TA371631 AP2A1 rabbit polyclonal antibody
100 ul
$310.00
TF81001 TurboFectin Transfection Reagent (1 mL in 1 vial)
1 ml in 1 vial
$530.00

Other products for "AP2 alpha or NM_014203"

Specifications
Specifications
Product Data
Locus ID 160
Synonyms ADTAA; AP2-ALPHA; CLAPA1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components AP2A1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 160). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_014203, NM_130787, NM_130787.1, NM_130787.2, NM_014203.1, NM_014203.2, BC014214, NM_014203.3, NM_130787.3
UniProt ID O95782
Summary This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation
Qureshi, Kaur, Hou et al
J. Biol. Chem. (2012) 287 (12), 9429-40 DOI: 10.1074/jbc.M111.304329
Cited by 8
AI Summary: OriGene’s shRNA targeting AP-2 (co-expressing RFP) was used in this study to investigate the role of clathrin-mediated endocytosis in CTLA-4 trafficking during T cell activation.
Snippet: shRNA targeting AP-2 and co-expressing RFP were purchased from Origene. ... CTLA-4 has been reported to be delivered to the cell surface from secretory lysosomes;however, its relatively short half-life makes it questionable whether this would be a storage compartment of the
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products