ARFGAP3 Human shRNA Plasmid Kit (Locus ID 26286)
Specifications
| Product Data | |
| Locus ID | 26286 |
|---|---|
| Synonyms | ARFGAP1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | ARFGAP3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 26286). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001142293, NM_014570, NM_014570.1, NM_014570.2, NM_014570.3, NM_014570.4, NM_001142293.1, BC005122, BC041383, NM_001142293.2 |
| UniProt ID | Q9NP61 |
| Summary | The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. provided by RefSeq, Nov 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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