BMAL1 (ARNTL) Human shRNA Plasmid Kit (Locus ID 406)
SKU
TR314656
ARNTL - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 406 |
|---|---|
| Synonyms | bHLHe5; BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | ARNTL - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 406). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001030272, NM_001030273, NM_001178, NM_001297719, NM_001297722, NM_001297724, NM_001351804, NM_001351805, NM_001351806, NM_001351807, NM_001351808, NM_001351809, NM_001351810, NM_001351811, NM_001351812, NM_001351813, NM_001351814, NM_001351815, NM_001351816, NM_001351817, NM_001351818, NM_001351819, NM_001351820, NM_001351821, NM_001351822, NM_001351823, NM_001351824, NR_147785, NR_147786, NR_147787, NR_147788, NR_147789, NR_147790, NR_147791, NM_001030273.1, NM_001030273.2, NM_001178.1, NM_001178.2, NM_001178.3, NM_001178.4, NM_001178.5, NM_001030272.1, NM_001030272.2, NM_001297724.1, NM_001297719.1, NM_001297722.1, BC016674, BC016674.1, BC041129, BC041129.1, BC031214, NM_001297719.2 |
| UniProt ID | O00327 |
| Summary | The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Circadian Modulation of 8-Oxoguanine DNA Damage Repair
Manzella, Bracci, Strafella et al
Sci Rep (2015) 5, 13752 DOI: 10.1038/srep13752
Manzella, Bracci, Strafella et al
Sci Rep (2015) 5, 13752 DOI: 10.1038/srep13752
Cited by 74
AI Summary: OriGene’s total RNA isolation kit was used to extract RNA for gene expression analysis, enabling the researchers to assess circadian variations in Ogg1 expression in the study.
Snippet: Gene expression analysis. The isolation of total RNA was performed (OriGene, Rockville, MD, USA) according to the manufacturer's instructions. RNA quality and quantification were evaluated with a Nanodrop 1000 spectrophotometer (Thermo Scientific, Wilmington ... Cite SaveSaving
Showing 1-1 of 1 papers.
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