ATP7B Human shRNA Plasmid Kit (Locus ID 540)
SKU
TR314561
ATP7B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 540 |
|---|---|
| Synonyms | PWD; WC1; WD; WND |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | ATP7B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 540). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_000053, NM_001005918, NM_001243182, NM_001330578, NM_001330579, NM_000053.1, NM_000053.2, NM_000053.3, NM_001005918.1, NM_001005918.2, NM_001243182.1, BC117200, BC143973, BC143974, BC143975, BC143976, NM_001005918.3, NM_000053.4 |
| UniProt ID | P35670 |
| Summary | This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. provided by RefSeq, Dec 2019 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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