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BCAR1 Human shRNA Plasmid Kit (Locus ID 9564)

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SKU
TR314502
BCAR1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 9564
Synonyms CAS; CAS1; CASS1; CRKAS; P130Cas
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components BCAR1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 9564). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001170714, NM_001170715, NM_001170716, NM_001170717, NM_001170718, NM_001170719, NM_001170720, NM_001170721, NM_014567, NM_014567.1, NM_014567.2, NM_014567.3, NM_001170721.1, NM_001170720.1, NM_001170719.1, NM_001170718.1, NM_001170715.1, NM_001170716.1, NM_001170717.1, NM_001170714.1, BC062556, BC062556.1, BC014402, NM_001170719.3, NM_001170718.3, NM_001170715.3, NM_001170717.3, NM_001170721.2, NM_001170720.3, NM_001170714.3, NM_001170716.3, NM_014567.5
UniProt ID P56945
Summary The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. provided by RefSeq, Sep 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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