BMF Human shRNA Plasmid Kit (Locus ID 90427)
SKU
TR314463
BMF - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 90427 |
|---|---|
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | BMF - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 90427). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001003940, NM_001003942, NM_001003943, NM_033503, NM_001003940.1, NM_033503.1, NM_033503.2, NM_033503.3, NM_001003942.1, NM_001003943.1, NM_001003943.2, BC070043, BC070043.1, BC060783, BC069328, BC069505, BC104983, BC104985, NM_001003943.3, NM_001003940.2, NM_033503.4 |
| UniProt ID | Q96LC9 |
| Summary | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Bmf Facilitates Protein Degradation and Reduces Beclin1 Ubiquitination to Inhibit Autophagy Independent of mTOR
Delgado-Vergas, Fort, Tassew et al
bioRxiv (2020)
Delgado-Vergas, Fort, Tassew et al
bioRxiv (2020)
Snippet: Retroviral silencing vector encoding for human Bmf short hairpin RNA (shRNA) and control vector were used. Bmf-specific shRNA plasmids and control plasmids were purchased from OriGene (OriGene Technologies, Inc.) and were packaged into retroviral particles using Phoenix cells as specified by the manufacturer’s instructions. …
Showing 1-1 of 1 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
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