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CAB39L Human shRNA Plasmid Kit (Locus ID 81617)

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SKU
TR314249
CAB39L - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 81617
Synonyms antigen MLAA-34; bA103J18.3; calcium binding protein 39-like; FLJ12577; MO2L; MO2L, FLJ12577, bA103J18.3, RP11-103J18.3; MO25-BETA; OTTHUMP00000018410; RP11-103J18.3; sarcoma antigen NY-SAR-79; U937-associated antigen
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components CAB39L - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 81617). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC010993, NM_001031724, NM_001079670, NM_001287337, NM_001287338, NM_001287339, NM_030925, NM_030925.1, NM_030925.2, NM_030925.3, NM_001079670.1, NM_001079670.2, NM_001287337.1, NM_001287338.1, NM_001287339.1, BC010993.2, NM_001031724.1, NM_001079670.3, NM_030925.4
UniProt ID Q9H9S4
Summary Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1 (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Metformin-induced ablation of microRNA 21-5p releases Sestrin-1 and CAB39L antitumoral activities
Pulito, Mori, Sacconi et al
Cell Discov (2017) 3, 17022 DOI: 10.1038/celldisc.2017.22
AI Summary: OriGene products, specifically the full-length 3′-UTR clones of the human CAB39L and SESN1 genes, were used to construct luciferase reporter assays that helped elucidate how metformin-induced downregulation of miR-21-5p enhances the antitumoral activities of these genes.
Snippet: The full-length 3′-UTR of the human CAB39L and SESN1 genes (OriGene, Rockville, MD, USA) were amplified and inserted downstream of the Renilla luciferase gene into the Not I site of the dual luciferase reporter plasmid psiCHECK-2 (Promega)
FigureFigureFigure
Showing 1-1 of 1 papers.
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