FLASH (CASP8AP2) Human shRNA Plasmid Kit (Locus ID 9994)
Specifications
| Product Data | |
| Locus ID | 9994 |
|---|---|
| Synonyms | CED-4; FLASH; RIP25 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | CASP8AP2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 9994). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001137667, NM_001137668, NM_012115, NM_012115.1, NM_012115.2, NM_012115.3, NM_001137667.1, NM_001137668.1, BC132828, BC132830, BC012574, BC027850, BC029386, BC042577, BC056685, BC150274, NM_012115.4, NM_001137668.2, NM_001137667.2 |
| UniProt ID | Q9UKL3 |
| Summary | This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.provided by RefSeq, Nov 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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