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CHRNA3 Human shRNA Plasmid Kit (Locus ID 1136)

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SKU
TR313921
CHRNA3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 1136
Synonyms BAIPRCK; LNCR2; NACHRA3; PAOD2
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components CHRNA3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 1136). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq BC006114, NM_000743, NM_001166694, NR_046313, NM_000743.1, NM_000743.2, NM_000743.3, NM_000743.4, NM_001166694.1, BC006114.1, BC000513, BC001642, BC002996, BC098443, BM666615, NM_001166694.2
UniProt ID P32297
Summary This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. provided by RefSeq, Nov 2009
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Molecular mechanisms of synergy of corneal muscarinic and nicotinic acetylcholine receptors in upregulation of E-cadherin expression
Chernyavsky, Galitovskiy, Grando
Int. Immunopharmacol. (2015)
Cited by 12
AI Summary: OriGene products contributed to this study by providing predesigned and tested shRNAs targeting human M3 and M4 muscarinic acetylcholine receptors and α3, α7, and α9 nicotinic acetylcholine receptor subunits, as well as a scrambled shRNA negative control, which were used to investigate the roles of these receptors in E-cadherin expression.
Snippet: The predesigned and tested small hairpin RNA (shRNA) targeting human M 3 and M 4 mAChRs and α3, α7 and α9 nAChR subunits as well as scrambled shRNA (negative control;shRNA-NC) were purchased from OriGene Technologies (Rockville, MD). ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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