CIRBP Human shRNA Plasmid Kit (Locus ID 1153)
Specifications
| Product Data | |
| Locus ID | 1153 |
|---|---|
| Synonyms | CIRP |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | CIRBP - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 1153). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001280, NM_001300815, NM_001300829, NR_023312, NR_023313, NM_001280.1, NM_001280.2, NM_001300815.1, NM_001300829.1, BC000901, BC000901.1, BC000403, BM706055, NM_001300829.2, NM_001300815.2 |
| UniProt ID | Q14011 |
| Summary | Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3' UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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