DECTIN 2 (CLEC6A) Human shRNA Plasmid Kit (Locus ID 93978)
Specifications
| Product Data | |
| Locus ID | 93978 |
|---|---|
| Synonyms | CLEC4N; CLECSF10; dectin-2; hDECTIN-2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | CLEC6A - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 93978). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001007033, NM_001317999, NM_001007033.1, BC132933, BC132935, NM_001007033.2 |
| UniProt ID | Q6EIG7 |
| Summary | The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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