Cathepsin D (CTSD) Human shRNA Plasmid Kit (Locus ID 1509)
Specifications
| Product Data | |
| Locus ID | 1509 |
|---|---|
| Synonyms | CLN10; CPSD; HEL-S-130P |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | CTSD - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 1509). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001909, NM_001909.1, NM_001909.2, NM_001909.3, NM_001909.4, BC016320, BC016320.2, BC001574, BM762986, BM976200, NM_001909.5 |
| UniProt ID | P07339 |
| Summary | This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. provided by RefSeq, Nov 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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