Cullin 4B (CUL4B) Human shRNA Plasmid Kit (Locus ID 8450)
Specifications
| Product Data | |
| Locus ID | 8450 |
|---|---|
| Synonyms | CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | CUL4B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 8450). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001079872, NM_003588, NM_001330624, NM_003588.1, NM_003588.2, NM_003588.3, NM_001079872.1, BC036216, BC036216.1, NM_001369145, NM_001079872.2 |
| UniProt ID | Q13620 |
| Summary | This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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