DKC1 Human shRNA Plasmid Kit (Locus ID 1736)
Specifications
| Product Data | |
| Locus ID | 1736 |
|---|---|
| Synonyms | CBF5; DKC; DKCX; NAP57; NOLA4; XAP101 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | DKC1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 1736). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001142463, NM_001288747, NM_001363, NR_110021, NR_110022, NR_110023, NM_001363.1, NM_001363.2, NM_001363.3, NM_001363.4, NM_001142463.1, NM_001142463.2, NM_001288747.1, BC009928, BC010015, NM_001363.5, NM_001142463.3 |
| UniProt ID | O60832 |
| Summary | This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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