DKC1 Human shRNA Plasmid Kit (Locus ID 1736)

SKU
TR313466
DKC1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 1736
Synonyms CBF5; DKC; DKCX; NAP57; NOLA4; XAP101
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components DKC1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 1736). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001142463, NM_001288747, NM_001363, NR_110021, NR_110022, NR_110023, NM_001363.1, NM_001363.2, NM_001363.3, NM_001363.4, NM_001142463.1, NM_001142463.2, NM_001288747.1, BC009928, BC010015, NM_001363.5, NM_001142463.3
UniProt ID O60832
Summary This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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