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EDG3 (S1PR3) Human shRNA Plasmid Kit (Locus ID 1903)

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SKU
TR313299
S1PR3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
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Specifications
Specifications
Product Data
Locus ID 1903
Synonyms EDG-3; EDG3; LPB3; S1P3
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components S1PR3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 1903). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_005226, NM_005226.1, NM_005226.2, NM_005226.3, BC060827, BC060827.1, BC069579, BM990167, NM_005226.4
UniProt ID Q99500
Summary This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC/Ca2+ signaling pathways
Yoon, Hong, Moon et al
Blood (2008) 112 (4), 1129-38 DOI: 10.1182/blood-2007-11-125203
Cited by 133
AI Summary: In this study, OriGene’s S1P1 and S1P3 siRNA products were used to down-regulate S1P receptor expression in human lymphatic endothelial cells, helping to demonstrate the critical role of S1P1 in S1P-mediated lymphangiogenesis.
Showing 1-1 of 1 papers.
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