EI24 Human shRNA Plasmid Kit (Locus ID 9538)
Specifications
| Product Data | |
| Locus ID | 9538 |
|---|---|
| Synonyms | EPG4; PIG8; TP53I8 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | EI24 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 9538). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001007277, NM_001290135, NM_004879, NR_110769, NR_110770, NM_001330419, NM_004879.1, NM_004879.2, NM_004879.3, NM_004879.4, NM_001007277.1, NM_001290135.1, BC002390, BC002390.2, BC029333, BM450796, BM467354, NM_004879.5, NM_001290135.2 |
| UniProt ID | O14681 |
| Summary | This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. provided by RefSeq, Feb 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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