EI24 Human shRNA Plasmid Kit (Locus ID 9538)

SKU
TR313270
EI24 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*
Specifications
Specifications
Product Data
Locus ID 9538
Synonyms EPG4; PIG8; TP53I8
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components EI24 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 9538). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001007277, NM_001290135, NM_004879, NR_110769, NR_110770, NM_001330419, NM_004879.1, NM_004879.2, NM_004879.3, NM_004879.4, NM_001007277.1, NM_001290135.1, BC002390, BC002390.2, BC029333, BM450796, BM467354, NM_004879.5, NM_001290135.2
UniProt ID O14681
Summary This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. provided by RefSeq, Feb 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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