EP300 Human shRNA Plasmid Kit (Locus ID 2033)
SKU
TR313197
EP300 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 2033 |
|---|---|
| Synonyms | KAT3B; MKHK2; p300; RSTS2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | EP300 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 2033). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001429, NM_001429.1, NM_001429.2, NM_001429.3, BC053889, BC172280, NM_001362843, NM_001429.4 |
| UniProt ID | Q09472 |
| Summary | This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
ANALYSIS OF THE UPSTREAM SIGNALLING PATHWAY CONTROLLING DELTANP63ALPHA PROTEIN STABILITY AND FUNCTION
Restelli
Thesis (2014)
Restelli
Thesis (2014)
Snippet: All expression vectors encoding p63 cDNAs, p300 cDNAs, c-Abl have been previously described (42, 43, 47, 59). The shRNA against p300 (shp300) and control shRNA (shLuc) were purchased from Origene company. Cite SaveSaving
Showing 1-1 of 1 papers.
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