FBXO22 Human shRNA Plasmid Kit (Locus ID 26263)
Specifications
| Product Data | |
| Locus ID | 26263 |
|---|---|
| Synonyms | FBX22; FISTC1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | FBXO22 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 26263). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC039024, NM_012170, NM_147188, NR_037623, NM_147188.1, NM_147188.2, NM_012170.1, NM_012170.2, NM_012170.3, BC039024.1, BC041691, BC041691.1, BC020204, BC032540, NM_147188.3 |
| UniProt ID | Q8NEZ5 |
| Summary | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2010 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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