FRS2 Human shRNA Plasmid Kit (Locus ID 10818)
Specifications
| Product Data | |
| Locus ID | 10818 |
|---|---|
| Synonyms | FRS1A; FRS2A; FRS2alpha; SNT; SNT-1; SNT1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | FRS2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 10818). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC036822, NM_001042555, NM_001278351, NM_001278353, NM_001278354, NM_001278355, NM_001278356, NM_001278357, NM_006654, NM_006654.1, NM_006654.2, NM_006654.3, NM_006654.4, NM_001042555.1, NM_001042555.2, NM_001278351.1, NM_001278353.1, NM_001278354.1, NM_001278355.1, NM_001278356.1, NM_001278357.1, BC021562, BC021562.1, NM_001278351.2, NM_001042555.3 |
| UniProt ID | Q8WU20 |
| Summary | Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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