GMDS Human shRNA Plasmid Kit (Locus ID 2762)
Specifications
| Product Data | |
| Locus ID | 2762 |
|---|---|
| Synonyms | GMD; SDR3E1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | GMDS - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 2762). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001253846, NM_001500, NM_001500.1, NM_001500.2, NM_001500.3, NM_001253846.1, BC000117, BC000117.1, BM665440, NM_001500.4 |
| UniProt ID | O60547 |
| Summary | GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).supplied by OMIM, Aug 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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