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HOXA11 Human shRNA Plasmid Kit (Locus ID 3207)

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SKU
TR312366
HOXA11 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 3207
Synonyms HOX1; HOX1I; RUSAT1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components HOXA11 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3207). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_005523, NM_005523.1, NM_005523.2, NM_005523.3, NM_005523.4, NM_005523.5, BC040948, BC040948.1, BC033706, NM_005523.6
UniProt ID P31270
Summary In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Knockdown of Hoxa11 in vivo in the uterosacral ligament and uterus of mice results in altered collagen and matrix metalloproteinase activity
Ma, Guess, Datar et al
Biol. Reprod. (2012) 86 (4), 100 DOI: 10.1095/biolreprod.111.093245
Cited by 36
AI Summary: OriGene's Hoxa11 shRNA plasmids were used to achieve targeted knockdown of Hoxa11 in mice, enabling the study of its effects on collagen and matrix metalloproteinase activity in reproductive tissues.
Snippet: In solution 2, four different Hoxa11 shRNA plasmids (OriGene Technologies Inc., Rockville, MD) were combined for use in Hoxa11 knockdown (KD) mice;an ... In the current study, we successfully knocked down Hoxa11 in the genital tract of mice and created a Hoxa11 and ECM
HoxA-11 and FOXO1A cooperate to regulate decidual prolactin expression: towards inferring the core transcriptional regulators of decidual genes
Lynch, Brayer, Gellersen et al
PLoS One (2009) 4 (9), e6845 DOI: 10.1371/journal.pone.0006845
Cited by 102
AI Summary: OriGene products contributed to this paper by providing the HoxA-11 and HoxA-10 expression plasmids, which were used to investigate their roles in regulating decidual prolactin expression.
FigureFigureFigure
Showing 1-2 of 2 papers.
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