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HOXB5 Human shRNA Plasmid Kit (Locus ID 3215)

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SKU
TR312357
HOXB5 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 3215
Synonyms HHO.C10; HOX2; Hox2.1; HOX2A; HU-1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components HOXB5 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3215). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_002147, NM_002147.1, NM_002147.2, NM_002147.3, BC004454, BC008940, BC117247
UniProt ID P09067
Summary This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

HOXB5 promotes malignant progression in pancreatic cancer via the miR-6732 pathway
Li, Wu, Jiang et al
Cell Cycle (2019) 19 (2), 233-245 DOI: 10.1080/15384101.2019.1707456
Cited by 35
AI Summary: OriGene products, specifically shRNAs targeting HOXB5 and related primer sequences, were used in this study to knock down HOXB5 expression and facilitate gene expression analysis, enabling the investigation of HOXB5’s role in pancreatic cancer progression.
Snippet: Knockdown using shRNAs shRNAs targeting HOXB5 were purchased from OriGene Biotechnology Company (Beijing, China) Related primer sequences were pur- chased from OriGene Biotechnology Company (Beijing, China). Reporter gene assays
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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