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IGFBP7 Human shRNA Plasmid Kit (Locus ID 3490)

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SKU
TR312216
IGFBP7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Other products for "IGFBP7 or NM_001253835"

Specifications
Specifications
Product Data
Locus ID 3490
Synonyms AGM; FSTL2; IBP-7; IGFBP-7; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components IGFBP7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3490). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001253835, NM_001553, NM_001553.1, NM_001553.2, NM_001253835.1, BC066339, BC066339.1, BC017201, NM_001553.3
UniProt ID Q16270
Summary This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). provided by RefSeq, Dec 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Insulin-like growth factor-binding protein 7 alters the sensitivity to interferon-based anticancer therapy in hepatocellular carcinoma cells
Tomimaru, Eguchi, Wada et al
Br J Cancer (2010) 102 (10), 1483-90 DOI: 10.1038/sj.bjc.6605669
Cited by 35
AI Summary: OriGene products contributed to this study by providing the IGFBP7 shRNA plasmid (Cat# TF314528) used to knock down IGFBP7 expression and the human IGFBP7 cDNA clone (Cat# RC201347) used for IGFBP7 overexpression in hepatocellular carcinoma cells, enabling the authors to investigate the role of IGFBP7 in interferon sensitivity.
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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