IRF3 Human shRNA Plasmid Kit (Locus ID 3661)
Specifications
| Product Data | |
| Locus ID | 3661 |
|---|---|
| Synonyms | IIAE7 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | IRF3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3661). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001197122, NM_001197123, NM_001197124, NM_001197125, NM_001197126, NM_001197127, NM_001197128, NM_001571, NR_045568, NM_001571.1, NM_001571.2, NM_001571.3, NM_001571.4, NM_001571.5, NM_001197125.1, NM_001197122.1, NM_001197127.1, NM_001197124.1, NM_001197123.1, NM_001197128.1, NM_001197126.1, BC071721, BC071721.1, BC009395, BC000660, BM477213, NM_001197126.2, NM_001197128.2, NM_001571.6, NM_001197124.2, NM_001197123.2, NM_001197127.2 |
| UniProt ID | Q14653 |
| Summary | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. provided by RefSeq, Sep 2020 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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