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IRF6 Human shRNA Plasmid Kit (Locus ID 3664)

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SKU
TR312109
IRF6 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Other products for "IRF6 or NM_001206696"

Specifications
Specifications
Product Data
Locus ID 3664
Synonyms LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components IRF6 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3664). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001206696, NM_006147, NM_006147.1, NM_006147.3, NM_001206696.1, BC014852, BC014852.1, NM_006147.4
UniProt ID O14896
Summary This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.provided by RefSeq, May 2011
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

TGFβ3 Regulates Periderm Removal through ΔNp63 in the Developing Palate
Hu, Liu, Li et al
J. Cell. Physiol. (2014)
Cited by 38
AI Summary: OriGene products pRS-shRNA-ΔNp63 and pRS-shRNA-IRF6 were used to specifically knock down ΔNp63 and IRF6 expression in primary MEE cells, enabling the authors to investigate the roles of these genes in periderm removal during palate development.
Snippet: MEE cells were treated with rTGFβ3 (5.0 ng/ml) for 24 hours. In order to block endogenous IRF6 and ΔNp63 mRNA levels, MEE cells were treated with pRS-shRNA- ΔNp63 and pRS-shRNA-IRF6 (OriGene Technologies Inc, Rockville, MD) for 24 hours followed by ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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