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KLF6 Human shRNA Plasmid Kit (Locus ID 1316)

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SKU
TR311885
KLF6 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 1316
Synonyms GBF, ZF9, BCD1, CPBP, PAC1, ST12, COPEB, DKFZp686N0199
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components KLF6 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 1316). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001008490, NM_001160124, NM_001160125, NM_001300, NR_027653, NM_001300.1, NM_001300.2, NM_001300.3, NM_001300.4, NM_001300.5, NM_001160125.1, NM_001160124.1, NM_001008490.1, BC000311, BC000311.2, BC004301, BC015987, BM544849, BM695496, NM_001160124.2, NM_001300.6
UniProt ID Q99612
Summary This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis. provided by RefSeq, May 2009
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression
Chen, Huang, Chu et al
J. Biol. Chem. (2011) 286 (12), 9968-76 DOI: 10.1074/jbc.M110.203240
Cited by 7
AI Summary: OriGene contributed to this study by providing the shRNA plasmid targeting KLF6, which was used to investigate the role of KLF6 in ERMA-induced apoptosis in prostate cancer cells.
Snippet: marks was mediated through transcriptional repression of histone deacetylases and H3 lysine 4 demethylases by down-regulating Sp1 ... Plasmids expressing shRNA for KLF6 and Sp1 were obtained from Origene Technologies (Rockville, MD) and Sigma-Aldrich, respectively.
Showing 1-1 of 1 papers.
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