LAMP2 Human shRNA Plasmid Kit (Locus ID 3920)
SKU
TR311794
LAMP2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
$883.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 3920 |
|---|---|
| Synonyms | CD107b; DND; LAMP-2; LAMPB; LGP-96; LGP110 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | LAMP2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3920). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001122606, NM_002294, NM_013995, NM_013995.1, NM_013995.2, NM_002294.1, NM_002294.2, NM_001122606.1, BC002965, BC002965.1, BC040653, NM_002294.3 |
| UniProt ID | P13473 |
| Summary | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Chaperone-mediated autophagy regulates proliferation by targeting RND3 in gastric cancer
Zhou, Yang, Fan et al
Autophagy (2016)
Zhou, Yang, Fan et al
Autophagy (2016)
Cited by 108
AI Summary: OriGene’s LAMP2A, LAMP2B, and LAMP2C plasmids (SC118738, SC127527, SC318864) and control plasmids (PCMV6XL5, PCMV6XL6) were used for transfection experiments to investigate the role of chaperone-mediated autophagy in gastric cancer cell proliferation.
Snippet: RND3 plasmid and control plasmid were transfected into cells as described previously.47 LAMP2A, LAMP2B and LAMP2C plasmids (OriGene, SC118738, SC127527 and SC318864) and their control plasmids (OriGene, PCMV6XL5 and PCMV6XL6) were used. The lentiviral vectors with shRNAs against LAMP2A were purchased from GeneChem Company, Shanghai, China (PIEL248064052). …
Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane
Damaghi, Tafreshi, Lloyd et al
Nat Commun (2015) 6, 8752 DOI: 10.1038/ncomms9752
Damaghi, Tafreshi, Lloyd et al
Nat Commun (2015) 6, 8752 DOI: 10.1038/ncomms9752
Cited by 185
AI Summary: OriGene products, including Trilencer-27 LAMP2 siRNA, LAMP2 shRNA plasmid (TR311794), and LAMP2 overexpression plasmid (RC221216), were used in this study to manipulate LAMP2 expression in breast cancer cell lines, enabling the authors to investigate the role of LAMP2 in cellular adaptation to chronic acidosis.
Snippet: … LAMP2 siRNAs (Trilencer-27: 27mer siRNA, Origene) were transfected using Lipofectamine RNAiMAX (Invitrogen # 13778030) according to the manufacturer’s protocol. To establish stable cell lines, the MCF-7 and MDA-MB-231 cells were infected with Plasmids expressing shRNA to LAMP2 (TR311794, Origene), LAMP2 overexpressing (RC221216, Origene) and red fluorescent protein or GFP expressing using Fugene 6 (Promega) at an early passage and were selected using 2 μg ml−1 puromycin (Sigma)
Showing 1-2 of 2 papers.
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