LMO1 Human shRNA Plasmid Kit (Locus ID 4004)

SKU TR311708

LMO1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided

Product Data

• Locus ID: 4004
• Synonyms: RBTN1; RHOM1; TTG1
• Vector: pRS
• E. coli Selection: Ampicillin
• Format: Retroviral plasmids
• Components: LMO1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4004). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
• RefSeq: NM_001270428, NM_002315, NR_073006, NM_002315.1, NM_002315.2, NM_001270428.1, BC069793, BC069793.1, BC039512, BC069673, BC069752, BC096056, BC096057, BC096058, NM_001270428.2, NM_002315.3
• UniProt ID: P25800
• Summary: This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2012]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient