LRAT Human shRNA Plasmid Kit (Locus ID 9227)
Specifications
| Product Data | |
| Locus ID | 9227 |
|---|---|
| Synonyms | LCA14 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | LRAT - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 9227). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001301645, NM_004744, NM_004744.1, NM_004744.2, NM_004744.3, NM_004744.4, NM_001301645.1, BC031053, BC031053.1, NM_004744.5 |
| UniProt ID | O95237 |
| Summary | The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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