MBD4 Human shRNA Plasmid Kit (Locus ID 8930)
Specifications
| Product Data | |
| Locus ID | 8930 |
|---|---|
| Synonyms | MED1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MBD4 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 8930). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001276270, NM_001276271, NM_001276272, NM_001276273, NM_003925, NM_003925.1, NM_003925.2, NM_001276273.1, NM_001276272.1, NM_001276271.1, NM_001276270.1, BC011752, BC034463, NM_001276270.2, NM_001276272.2, NM_003925.3 |
| UniProt ID | O95243 |
| Summary | The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Jan 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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