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MFGE8 Human shRNA Plasmid Kit (Locus ID 4240)

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SKU
TR311492
MFGE8 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Other products for "MFGE8 or NM_001114614"

Specifications
Specifications
Product Data
Locus ID 4240
Synonyms BA46; EDIL1; HMFG; hP47; HsT19888; MFG-E8; MFGM; OAcGD3S; SED1; SPAG10
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components MFGE8 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4240). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001114614, NM_001310319, NM_001310320, NM_001310321, NM_005928, NM_005928.1, NM_005928.2, NM_005928.3, NM_001114614.1, NM_001114614.2, BC003610, NM_005928.4, NM_001114614.3
UniProt ID Q08431
Summary This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Endometrial MFG-E8 regulates TGF-β induced EMT promoting trophoblast invasion and implantation
Yu, Hu, Sullivan et al
Reproduction (2016)
AI Summary: OriGene products contributed to this study by providing gene-specific shRNA expression vectors in retroviral silencing plasmids and TurboFectin 8.0 transfection reagent, which were used to knock down MFG-E8 in HEC-1A cells to investigate its role in TGF-β induced EMT.
Snippet: shRNA constructs containing 4 vials of gene- specific shRNA expression vectors in retroviral 202 silencing plasmid (OriGene, Rockville, MD), respectively. ... HEC-1A cells were transfected with the vectors using 204 TurboFectin 8.0 transfection reagent (OriGene, Rockville ... Cite SaveSaving
Showing 1-1 of 1 papers.
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