MGP Human shRNA Plasmid Kit (Locus ID 4256)
Specifications
| Product Data | |
| Locus ID | 4256 |
|---|---|
| Synonyms | GIG36; MGLAP; NTI |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MGP - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4256). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_000900, NM_001190839, NM_000900.1, NM_000900.2, NM_000900.3, NM_000900.4, NM_001190839.1, NM_001190839.2, BC093078, BC005272, BC070314, NM_001190839.3, NM_000900.5 |
| UniProt ID | P08493 |
| Summary | This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia. provided by RefSeq, Sep 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Kuzontkoski, Mulligan-Kehoe, Harris et al
Oncogene (2010) 29 (26), 3793-802 DOI: 10.1038/onc.2010.147
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