MMP8 Human shRNA Plasmid Kit (Locus ID 4317)
Specifications
| Product Data | |
| Locus ID | 4317 |
|---|---|
| Synonyms | CLG1; HNC; MMP-8; PMNL-CL |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MMP8 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4317). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001304441, NM_001304442, NM_002424, NM_002424.2, BC074989, BC074989.2, BC074988, BC144094, NM_002424.3 |
| UniProt ID | P22894 |
| Summary | This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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