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MPG Human shRNA Plasmid Kit (Locus ID 4350)

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SKU
TR311419
MPG - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 4350
Synonyms AAG; ADPG; anpg; APNG; CRA36.1; MDG; Mid1; PIG11; PIG16
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components MPG - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4350). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001015052, NM_001015054, NM_002434, NM_001015054.1, NM_001015054.2, NM_001015052.1, NM_001015052.2, NM_002434.1, NM_002434.2, NM_002434.3, BC014991, BC014991.1, BM796301, NM_002434.4, NM_001015052.3
UniProt ID P29372
Summary Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Germ-line variants of human N-methylpurine DNA glycosylase show impaired DNA repair activity and facilitate 1,N6 ethenoadenine induced mutations
Adhikari, Chetram, Woodrick et al
J. Biol. Chem. (2014)
AI Summary: OriGene's pRS-shMPG and pRS-scramble vectors were used to generate cells with reduced or control levels of hMPG, enabling the study of how specific hMPG gene variants affect DNA repair activity and mutation rates.
Snippet: Retrovirus-packaging (SD3443) cells were transfected with either pRS-shMPG or pRS- scramble vector, using Fugene (Promega, Madison, WI) transfection reagent, following the manufacture's protocol (OriGene, Rockville, MD). ... Cite SaveSaving
Showing 1-1 of 1 papers.
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