MRPS27 Human shRNA Plasmid Kit (Locus ID 23107)
Specifications
| Product Data | |
| Locus ID | 23107 |
|---|---|
| Synonyms | MRP-S27; S27mt |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MRPS27 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 23107). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001286748, NM_001286751, NM_015084, NM_015084.1, NM_015084.2, NM_001286751.1, NM_001286748.1, BC064902, BC064902.1, BC003632, BC011818, BC030521, BM995930, NM_001286748.2, NM_015084.3, NM_001286751.2 |
| UniProt ID | Q92552 |
| Summary | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3). Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Nov 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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