MSH2 Human shRNA Plasmid Kit (Locus ID 4436)
Specifications
| Product Data | |
| Locus ID | 4436 |
|---|---|
| Synonyms | COCA1; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; MMRCS2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MSH2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4436). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_000251, NM_001258281, NM_000251.1, NM_000251.2, NM_001258281.1, BC021566, BC021566.1, BC001122, BC012599, NM_000251.3 |
| UniProt ID | P43246 |
| Summary | This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Apr 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Schwan
thesis (2015)
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