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NRF1 Human shRNA Plasmid Kit (Locus ID 4899)

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SKU
TR311098
NRF1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 4899
Synonyms ALPHA-PAL
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components NRF1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4899). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001040110, NM_001293163, NM_001293164, NM_005011, NM_001040110.1, NM_005011.1, NM_005011.2, NM_005011.3, NM_005011.4, NM_001293164.1, NM_001293163.1, BC016925, BM449724, BM993780, NM_001293163.2, NM_001293164.2, NM_001040110.2
UniProt ID Q16656
Summary This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. provided by RefSeq, May 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
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file-alt Citations

Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells
Roy, Pratheeshkumar, Son et al
Toxicol. Appl. Pharmacol. (2016) 307, 81-90 DOI: 10.1016/j.taap.2016.07.016
Cited by 34
AI Summary: OriGene products contributed to this study by providing Nrf2, SOD2, and catalase shRNAs, which were used to selectively silence these genes and investigate their roles in Cr(VI)-induced inflammatory responses.
Snippet: 2014). Nrf2, SOD2 and catalase shRNAs were purchased from Origene (Rockville, MD) (Son et al., 2014 and Son et al., 2015a). Transfections were performed using Lipofectamine 2000 (Invitrogen) according to the manufacturer's protocol. ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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