OGDH Human shRNA Plasmid Kit (Locus ID 4967)
Specifications
| Product Data | |
| Locus ID | 4967 |
|---|---|
| Synonyms | AKGDH; E1k; KGD1; OGDC; OGDH2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | OGDH - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 4967). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC009580, NM_001003941, NM_001165036, NM_002541, NM_002541.1, NM_002541.2, NM_002541.3, NM_001003941.1, NM_001003941.2, NM_001165036.1, BC009580.1, BC004964, BC004964.1, BC014617, BC128549, BC128550, BM998792, NM_001363523, NM_001003941.3, NM_001165036.2, NM_002541.4 |
| UniProt ID | Q02218 |
| Summary | This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.provided by RefSeq, Sep 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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