PARL Human shRNA Plasmid Kit (Locus ID 55486)
Specifications
| Product Data | |
| Locus ID | 55486 |
|---|---|
| Synonyms | PRO2207; PSARL; PSARL1; PSENIP2; RHBDS1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PARL - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 55486). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001037639, NM_001037640, NM_001324436, NM_001324437, NM_001324438, NM_018622, NR_136893, NM_001037639.1, NM_001037639.2, NM_018622.1, NM_018622.2, NM_018622.3, NM_018622.4, NM_018622.5, NM_018622.6, BC003653, BC003653.1, BC014058, BC014058.2, NM_018622.7, NM_001037639.3 |
| UniProt ID | Q9H300 |
| Summary | This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease. provided by RefSeq, May 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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