PFKFB1 Human shRNA Plasmid Kit (Locus ID 5207)
Specifications
| Product Data | |
| Locus ID | 5207 |
|---|---|
| Synonyms | F6PK; HL2K; PFRX |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PFKFB1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5207). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001271804, NM_001271805, NM_002625, NR_073450, NM_002625.1, NM_002625.2, NM_002625.3, NM_001271805.1, NM_001271804.1, BC096078, BC096077, BC096079, NM_001271804.2, NM_002625.4 |
| UniProt ID | P16118 |
| Summary | This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Nov 2012 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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