PHOX2A Human shRNA Plasmid Kit (Locus ID 401)
Specifications
| Product Data | |
| Locus ID | 401 |
|---|---|
| Synonyms | ARIX; CFEOM2; FEOM2; NCAM2; PMX2A |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PHOX2A - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 401). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_005169, NM_005169.1, NM_005169.2, NM_005169.3, BC041564, BC041564.1, NM_005169.4 |
| UniProt ID | O14813 |
| Summary | The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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