PLA2G1B Human shRNA Plasmid Kit (Locus ID 5319)
Specifications
| Product Data | |
| Locus ID | 5319 |
|---|---|
| Synonyms | PLA2; PLA2A; PPLA2 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PLA2G1B - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5319). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | BC005386, NM_000928, NM_000928.1, NM_000928.2, BC005386.1, BC013384, BC106725, BC106726, NM_000928.3 |
| UniProt ID | P04054 |
| Summary | This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. provided by RefSeq, Aug 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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