PPOX Human shRNA Plasmid Kit (Locus ID 5498)
Specifications
| Product Data | |
| Locus ID | 5498 |
|---|---|
| Synonyms | PPO; V290M; VP |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PPOX - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5498). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_000309, NM_001122764, NM_001350128, NM_001350129, NM_001350130, NM_001350131, NM_000309.1, NM_000309.2, NM_000309.3, NM_000309.4, NM_001122764.1, NM_001122764.2, BC002357, NM_001365398, NM_001365399, NM_001365400, NM_001365401, NM_001122764.3, NM_000309.5 |
| UniProt ID | P50336 |
| Summary | This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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