SAP1 (PTPRH) Human shRNA Plasmid Kit (Locus ID 5794)
Specifications
| Product Data | |
| Locus ID | 5794 |
|---|---|
| Synonyms | R-PTP-H; SAP1 |
| Vector | pRS |
| E. coli Selection | Ampicillin |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | PTPRH - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 5794). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
| RefSeq | NM_001161440, NM_002842, NM_002842.1, NM_002842.2, NM_002842.3, NM_002842.4, NM_001161440.1, NM_001161440.2, BC111715, BC111716, NM_002842.5, NM_001161440.3 |
| UniProt ID | Q9HD43 |
| Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jun 2009 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Fox, Ismail, Azad et al
EMBO J (2010) 29 (22), 3853-68 DOI: 10.1038/emboj.2010.244
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