PWP1 Human shRNA Plasmid Kit (Locus ID 11137)

SKU
TR310031
PWP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 11137
Synonyms IEF-SSP-9502
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components PWP1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 11137). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001317962, NM_001317963, NM_007062, NM_007062.1, NM_007062.2, BC001652, BC001652.2, BC000067, BC010921, BC032127, BC040135, BC046144, NM_007062.3
UniProt ID Q13610
Summary The protein encoded by this gene contains several WD-40 repeats and is found mostly in the nucleus. The expression and localization of this protein are cell cycle dependent. Expression of this gene is upregulated in pancreatic adenocarcinoma. Three transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

PWP1 Promotes the Malignant Phenotypes of Lung Cancer Cells by Interacting with DVL2 and Merlin
Wei, Li, Luo et al
Onco Targets Ther (2020) 13, 10025-10037 DOI: 10.2147/OTT.S263815
AI Summary: OriGene products, including the empty PCMV6 vector (#PS-100001), MYC/DDK-PCMV6-PWP1 plasmid (#RC200892), and shPWP1 plasmid (#TR310031), were used for gene overexpression and knockdown experiments to investigate the functional role of PWP1 in lung cancer cells in this study.
Snippet: week. Plasmid Construction and Transfection. The empty PCMV6 vector (#PS-100001), MYC/DDK-PCMV6-PWP1 plasmid (#RC200892), and shPWP1 plasmid (#TR310031) were purchased from Origene (Rockville, MD, USA)
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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