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DENND5A Human shRNA Plasmid Kit (Locus ID 23258)

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SKU
TR309985
DENND5A - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
  $883.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 23258
Synonyms DEE49; EIEE49; RAB6IP1
Vector pRS
E. coli Selection Ampicillin
Mammalian Cell Selection Puromycin
Format Retroviral plasmids
Components DENND5A - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 23258). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq NM_001243254, NM_015213, NM_001348748, NM_001348749, NM_001348750, NR_145966, NM_015213.1, NM_015213.2, NM_015213.3, NM_001243254.1, BC071596, BC071596.1, BC005100, BC009354, BC018797, NM_001243254.2, NM_015213.4
UniProt ID Q6IQ26
Summary This gene encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene are associated with early infantile epileptic encephalopathy-49. provided by RefSeq, Feb 2017
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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